SILICON
NANOSTRUCTURES FOR BIOLOGICAL APPLICATIONS
1Anca Angelescu,
1Irina Kleps, 1Mihaela Miu, 1Monica
Simion, 2Livia Zdrentu,
2Stefana Petrescu, 1Teodora Neghina, 1Adina
Bragaru
1National
Institute for Research and Development in Microtechnologies
(IMT-Bucharest), Centre of Nanotechnologies, P.O.Box 38-160, 023573,
Bucharest, Romania;
fax:
4021.4908238, e-mail: [email protected]
2
Institute of Biochemistry, Splaiul Independentei 296, Bucharest,
Romania
In this paper, the properties of
nanostructured porous silicon (PS) as a material suitable for
bio-medicine applications are studied. The PS capacity to be a
biomaterial was investigated by studying its biocompatibility,
bioactivity and biodegrability.
Different research directions were
developed:
(i)
PS functionalisation for ensuring the biocompatible
interface with different biological materials and for achieving a
bioactive surface;
(ii)
PS impregnation with drugs/microelements for in vitro
resorption and the slow release of minerals;
(iii)
PS bioactivity is proved by the hydroxyapatite (HA)
nucleation on its surface.